Extreme Damage to Muscles from Prednisone – Muscle Pain
The Horror of Taking Prednisone
BY STEVE
June 2021: I’ve been off this junk for about 5 days is it normal for it to cause twitching and jello feeling legs? I went to the doctor and all she did was test my blood and said all is good.
September 2021: I contacted you several months ago. I have been going to neurology appointments for the weakness in my upper legs, spasms, twitching, and cramps for those last 3 or 4 months.
After so much testing NCS, EMG, MRI, ultrasound, and a bunch of other things. My team of 3 neuros came to a unanimous cause was most likely the prednisone. I thought that I was only given 500mg IV for 5 days, when in fact I got 500mg 2x a day for 5 days then high dose taper. This crap did extreme damage.
I’m happy to say I’m at the end of the tunnel and only have minor spasms and slight twitches.
Never again… Ever!
Recovering from Prednisone Muscle Side Effects
Yea It sent me into extreme health anxiety. A few Dr told me that prednisone hangs around in your system way longer than we think. I had it IV and oral for optic neuritis which turned out to be idiopathic.
All that strife for that Neuro said after ruling out MS it was most likely idiopathic and Nmo and Mog. Lumbar puncture, MRI of the brain and cervical and thoracic. It was a journey, one I’ll never go on again!
How Long Did it Take to Recover from Prednisone Muscle Pain?
The first dose was in mid-April 1000mg for 5days. Started on high dose taper 80mg all down to 10mg till the 2nd week of June. Didn’t feel good again till the last week of August when symptoms started tapering off. (Less weakness, less cramps, less spasms).
I still have some but it hasn’t affected me at all now. I think getting the final all clears with some good solid reassurance and a solid answers helped the psychological aspect of it a lot.
It was a long, mentally draining road.
Prednisone Taper Side Effects
So on the taper at 30mg, I became very dopey like I was in my body, but not really. A vertigo-like effect. A lot of weight loss like 13lbs. Very weird dreams and Tinnitus.
The Best Thing you can do while on Prednisone Taper
For god’s sake, don’t google your symptoms, because its not good! Let your Dr do the doctoring.

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