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Manage Prednisone Withdrawal – Getting Off Side Effects

Manage Prednisone Withdrawal – Getting Off Side Effects

Prednisone, a synthetic corticosteroid, is often prescribed to manage inflammation and autoimmune conditions. While it can be highly effective, discontinuing its use can present significant challenges due to withdrawal symptoms. This phenomenon, known as prednisone withdrawal syndrome or steroid withdrawal syndrome, can be more distressing than the side effects experienced while on the medication.

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Prednisone Withdrawal

Prednisone mimics the body’s natural hormone cortisol, which is crucial for various bodily functions. When you stop taking prednisone, your body needs time to adjust to the absence of this synthetic hormone, leading to withdrawal symptoms. These symptoms can vary greatly among individuals, influenced by genetic differences.

Common withdrawal symptoms include extreme fatigue, loss of energy, hypoglycemia (low blood sugar), hypotonia (reduced muscle strength), nausea, muscle and joint pain, sleep disturbances, and weight fluctuations. These symptoms can feel similar to having the flu and reflect the body’s adjustment to the hormonal changes.

Consulting a Healthcare Provider

If you experience these symptoms, it’s essential to consult a healthcare provider. The nonspecific nature of these symptoms means they could also indicate an underlying infection, which prednisone can mask. Ruling out infections is crucial before attributing symptoms solely to withdrawal.

The Taper Trap and How to Avoid It

Many individuals encounter the “taper trap” during the tapering process, often between doses of 10 mg, 5 mg, and 2.5 mg. For instance, if you successfully reduce your dosage from 20 mg to 15 mg to 10 mg but experience severe symptoms after dropping to 5 mg, it may be advisable to return to the 10 mg dose temporarily. This approach allows your body to adjust more gradually to the lower dosage.

The percentage drop in dosage is critical; a reduction from 10 mg to 5 mg represents a 50% decrease, which is substantial compared to earlier reductions. A more gradual tapering process can help manage withdrawal symptoms more effectively.

Prednisone Taper Chart

To facilitate a more manageable tapering process, consider using resources like a Prednisone Taper Chart. This can provide guidance on a slower and more deliberate tapering schedule, helping you track your progress and make informed decisions about dosage adjustments.

prednisone withdrawal

Prednisone Taper Chart

Receive a free printable Prednisone Taper Chart to help you know when to taper down in prednisone dose. This does not substitute your doctor’s prescription.

Dr. Megan Milne, PharmD, BCACP

Dr. Megan Milne, PharmD, BCACP, is an award-winning clinical pharmacist board certified in the types of conditions people take prednisone for. Dr. Megan had to take prednisone herself for an autoimmune condition so understands what it feels like to suffer prednisone side effects and made it her mission to counteract them as the Prednisone Pharmacist.

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