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9+ Dangers of Prednisone

9+ Dangers of Prednisone

Prednisone, a commonly prescribed corticosteroid, is often met with apprehension due to its potential side effects—a phenomenon known as “corticophobia.” This fear is not only prevalent among patients but also among healthcare professionals, including pharmacists, who are acutely aware of the medication’s risks. In this blog post, find out the 9+ dangers or worst side effects of prednisone, ranked from least to most severe, and explore strategies to manage them effectively.

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9+ Dangers – Worst Side Effect Of Prednisone

9th: Insomnia – The Sleep Thief

Insomnia, the ninth side effect, is frequently discussed on social media. It disrupts the body’s healing process by depriving individuals of restorative sleep, which is crucial for recovery. The discomfort of sleepless nights can complicate the treatment of the underlying condition for which prednisone is prescribed.

8th: Skin Thinning and Easy Bruising

Ranked eighth, skin thinning and easy bruising occur due to prednisone’s negative impact on collagen production. This makes the skin fragile and susceptible to injuries from minor impacts, akin to paper cuts, increasing the likelihood of tears and bruises.

7th: Increased Infection Risk

The seventh side effect is an increased risk of infections, particularly pneumonia. Prednisone suppresses the immune system, diminishing the body’s ability to combat infections. This is particularly concerning in the context of pneumonia, which can lead to severe health complications.

6th: Cardiovascular Disease

Prednisone can elevate blood pressure and cause arrhythmias, posing significant health risks. The potential for fatal outcomes from heart disease and pneumonia underscores the seriousness of these side effects.

5th: Hyperglycemia

As a glucocorticoid, prednisone can lead to hyperglycemia, characterized by elevated blood sugar levels. This can result in weight gain and the onset of diabetes, among other health complications.

4th: Bone Loss

Bone loss, or osteoporosis, is the fourth most dangerous side effect. Prednisone disrupts bone metabolism, leading to decreased levels of calcium and collagen, which are vital for maintaining bone density. This increases the risk of fractures and conditions such as avascular necrosis.

3rd: Mood Changes

Mood changes rank third among the side effects. Many individuals report significant shifts in their emotional state, experiencing anxiety, depression, and even psychosis. These mood alterations can severely impact a person’s quality of life and daily functioning.

2nd: Weight Gain

Although weight gain is not inherently dangerous, it is the second worst side effect due to its frustrating and challenging nature. Prednisone causes the body to retain sodium and redistributes fat, leading to unwanted weight gain that can feel uncontrollable.

Top Worst Side Effect:

MOON FACE

The most concerning side effect is “moon face,” characterized by a round, puffy appearance of the face and abdomen. This visible change can adversely affect self-esteem and confidence, as illustrated by the author’s personal anecdote about experiencing moon face while job hunting.

Empowering Management Strategies

To help mitigate these side effects, a comprehensive checklist is available, offering over 25 tips for managing the adverse effects of prednisone. This resource is designed to empower individuals to minimize the medication’s dangers. By understanding and addressing these side effects, patients can navigate their treatment with greater confidence and control.

Dr. Megan Milne, PharmD, BCACP

Dr. Megan Milne, PharmD, BCACP, is an award-winning clinical pharmacist board certified in the types of conditions people take prednisone for. Dr. Megan had to take prednisone herself for an autoimmune condition so understands what it feels like to suffer prednisone side effects and made it her mission to counteract them as the Prednisone Pharmacist.

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